Blocked isocyanates

ABSTRACT

A blocked polyisocyanate of the formulawhere R is an m valent aliphatic, cycloaliphatic, heterocyclic or aromatic residue;each Y, which may be the same or different, iswhere R1 is, or, when n is more than 1, each R1, which may be the same or different, is an alkyl, alkenyl, aralkyl, N-substituted carbamyl, phenyl, NO2, halogen orgroup where R2 is a C1-C4 alkyl group:n is 0, 1, 2 or 3, andm is an integer greater than 1 is useful in paint compositions.

This is a Division of application Ser. No. 08/434,678, filed May 4, 1995 now U.S. Pat. No. 5,986,033 which is a continuation of Ser. No. 08/237,929, filed May 4, 1994, now abandoned which is a division of Ser. No. 08/079,904 filed Jun. 23, 1993 now U.S. Pat. No. 5,352,755 which is a division of Ser. No. 07/930,455 filed Aug. 19, 1992 now U.S. Pat. No. 5,246,557 which is a continuation of Ser. No. 07/769,479 filed Oct. 1, 1991 abandoned which is a continuation of Ser. No. 07/525,713 filed May 21, 1990, now abandoned, which is a division of Ser. No. 06/892,898 filed Aug. 1, 1986 now U.S. Pat. No. 4,976,837 which is a continuation of Ser. No. 06/706,391, filed Feb. 27, 1985, abandoned.

The present invention relates to novel blocked polyisocyanates, methods for making them, coating and other compositions e.g. paints and elastomers, containing them and methods of electrodeposition of the coating compositions.

Blocked polyisocyanates are commonly used in paints which also contain active hydrogen containing compounds e.g. amines and alcohols. Certain of these paints can be electrophoretically or conventionally e.g. spray deposited onto the article to be coated and then subsequently hardened by heating, often referred to as stoving. During stoving the blocked polyisocyanates dissociate so that the isocyanate groups become available to react with the active hydrogen containing compounds leading to crosslinking and hardening of the paint.

Blocked polyisocyanates reacting with any active hydrogen containing compound for the purposes of curing by chain extension or crosslinking are also used in cross-linking acrylic resins for automotive priming and finishing, formulating one-pack elastomers and surface coatings which contain the blocked isocyanate and as a chain extender in a single storage stable package which, when cast, can be cured by application of temperatures above the unblocking temperature.

Blocked polyisocyanates are polyisocyanates in which each isocyanate group has reacted with a protecting or blocking agent to form a derivative which will dissociate on heating to remove the protecting or blocking agent and release the reactive isocyanate group.

Compounds already known and used as blocking agents for polyisocyanates include aliphatic, cyclo-aliphatic or aralkyl monobydric alcohols, hydroxylamines and ketoximes.

Currently used blocked polyisocyanates dissociate at temperatures of around 160° C. If a blocked polyisocyanate could be used which dissociated at a lower temperature but was still stable at ambient temperatures, then heat sensitive materials could be utilised and energy savings could be made. The blocked polyisocyanates of the present invention dissociate at a significantly lower temperature than those currently used and are easily made. The presence of a catalyst is preferred in order to increase the rate of reaction between the liberated polyisocyanate and the active hydrogen containing compound, especially if the active hydrogen group is —OH. The catalyst can be any catalyst known in the art, e.g. dibutyl tin dilaurate or triethylene diamine.

The present invention comprises a compound of the formula:

R—Y_(m)  (I)

where R is an m valent aliphatic, cycloaliphatic , heterocyclic or aromatic residue and each Y, which may be the same or different, is

where R₁ is, or, when n is more than 1, each R₁, which may be the same or different, is an alkyl, alkenyl, aralkyl, N-substituted carbamyl, phenyl, NO₂, halogen or

group where R₂ is a C₁-C₄ alkyl group,

n is 0, 1, 2 or 3

and m is an integer al, preferably 2-6.

When R₁ represents an alkyl or alkenyl group it preferably contains up to 4 carbon atoms. When it is an aralkyl group, it is preferred that the aryl portion is phenyl and that the alkyl portion contains 1 to 4 carbon atoms. When R₁ is a halogen, it is preferably chlorine or bromine.

The blocking agents used in the present invention are pyrazoles of the formula:

where R₁ and n are as defined above. Examples of the pyrazoles described include 3,5-dimethylpyrazole, 3-methylpyrazole, 4-nitro-3,5-dimethylpyrazole and 4-bromo-3,5-dimethylpyrazole.

The preferred blocking agent is 3,5-dimethylpyrazole.

Some of these pyrazoles can be made by converting acetylacetone (AA) into a derivative which will react with hydrazine to give the desired pyrazole e.g.

AA+Na+CH₂═CHCH₂Cl→Ac₂CHCH₂CH═CH₂

AA+Na+PhCH₂Cl→Ac₂CHCH₂Ph

AA+PhNCO→Ac₂CHCONHPh

The polyisocyanate which is to be blocked may be any organic polyisocyanate suitable for crosslinking compounds containing active hydrogen e.g. aliphatic including cycloaliphatic, aromatic, heterocyclic, and mixed aliphatic aromatic polyisocyanates containing 2, 3 or more isocyanate groups. The group R will normally be a hydrocarbon group but substitution e.g. by alkoxy groups is possible.

The isocyanate compound may be, for example, ethylene diisocyanate, propylene diisocyanate, tetramethylene diisocyanate, hexamethylene diisocyanate, decamethylene diisocyanate, dodecamethylene diisocyanate, 2,4,4-trimethylhexamethylene-1,6 diisocyanate, phenylene diisocyanate, tolylene or naphthylene diisocyanate, 4,4′-methylene-bis(phenyl isocyanate), 4,4′-ethylene-bis (phenyl isocyanate), ω,ω′-diisocyanato-1,3-dimethyl benzene, ω,ω′-diisocyanato-1,4-dimethyl cyclohexane, ω,ω′-diisocyanato-1,4-dimethyl benzene, ω,ω′-diisocyanato-1,3-dimetbylcyclohexane, 1-methyl-2,,4-diisocyanato cyclohexane, 4,4′-methylene-bis (cyclohexyl isocyanate), 3-isocyanato-methyl-3,5,5-trimethyl cyclohexyl isocyanate, dimer acid-diisocyanate, ω,ω′-diisocyanato-diethyl benzene, ω,ω′-diisocyanatodimethyl toluene, ω,ω′-diisocyanato-dietbyl toluene, fumaric acid-bis (2-isocyanato ethyl) ester or triphenyl-methane-triisocyanate, 1,4-bis-(2-isocyanato-prop-2yl) benzene, 1,3-bis-(2-isocyanato prop-2yl) benzene, but is preferably free from isocyanate groups directly attached to aromatic nuclei.

Use can also be made of polyisocyanates obtained by reaction of an excess amount of the isocyanate with a) water, b) a lower molecular weight polyol (e.g. m.w.≦300) or c) a medium molecular weight polyol, e.g. a polyol of greater than 300 and less than 8000 m.w., eg sucrose, or by the reaction of the isocyanate with itself to give an isocyanurate.

The lower molecular weight polyol comprises, for example, ethyleneglycol, propyleneglycol, 1,3-butylene glycol, neopentyl glycol, 2,2,4-trimethyl-1,3-pentane diol, hexamethylene glycol, cyclohexane dimethanol, hydrogenated bisphenol-A, trimethylol propane, trimethylol ethane, 1,2,6-hexane triol, glycerine, sorbitol or pentaerythritol.

The di- or poly-isocyanate obtained by the above reaction may have a biuret structure, or an allophanate group.

The blocked polyisocyanate of the formula I is formed by admixing the polyisocyanate

R(NCO)_(m)  (III)

with a sufficient quantity of a pyrazole of the formula:

such that the reaction product contains no free isocyanate groups and is a urea of formula I. This reaction is exothermic and since the reaction product will dissociate if the temperature is raised sufficiently, cooling may be required to keep the temperature of the reaction mixture down, preferably to 80° C. or less.

One use of blocked polyisocyanates is in electrophoretically deposited paints. The invention also comprises a paint composition comprising a pigment carrier containing active hydrogen groups, a pigment and a compound of the formula I.

These paints are usually composed of a pigment dispersed in an aqueous dispersion of a resin containing active hydrogen which is to be crosslinked by the polyisocyanate. Preferably the paint contains 0.5 to 2 blocked isocyanate groups per active hydrogen containing group. Suitable active hydrogen containing resins include polyamide-polyamine resins, e.g. the product from a dimer fatty acid and an aliphatic polyamine, carboxylic acid group containing acrylic resins, and tertiary amine group containing hydroxyacrylic resins and polymers thereof.

The total concentration of the dispersed solids will, of course, depend upon the process for which the paint is to be used. Various standard additives such as surface active agents, catalysts and anti-oxidants may also be incorporated.

The invention also comprises a method of electrodepositing onto substrates a paint composition as described above and then heating the deposited paint to cross link the pigment carrier.

The electrophoretic deposition process is well known and involves the use of a cathode and an anode in contact with a bath containing the paint. The surface to be coated is one of the electrodes. On applying a voltage, generally 1 to 3,000 volts, across the electrodes the paint is deposited over the chosen electrode.

The coated article is removed from the bath and stoved e.g. baked in an oven, in order to release the isocyanate groups which then react with the active hydrogen in the resin to crosslink and harden the coating. Using coating compositions according to this invention the temperature to which the coated article must be heated is generally 100 to 140° C., which is significantly lower than the temperatures required in current commercial processes of 160° C. or more.

An added advantage of the process of our invention is the ability to block polyisocyanates in the presence of alcoholic solvents, because pyrazoles are much more reactive than alcohols towards polyisocyanates. This also makes it possible to block polyisocyanates at temperatures lower than those used with compounds already known and used as blocking agents for polyisocyanates.

The following Examples illustrate the invention. All parts and percentages are by weight unless otherwise specified.

EXAMPLE 1

A mixture of 292.4 parts of Trixene L75 (which is a polyfunctional isocyanate made by the addition of toluene di-isocyanate and a mixture of trimethylolpropane and diethylene glycol, as a 75% solution in ethyl acetate) and 105.8 parts of ethyl acetate is stirred while 94.9 parts of 3,5-dimethylpyrazole is added during 5 minutes, the temperature rising from 23° C. to 55° C. After 2¾ hours the temperature falls to 27° C. The I.R. Spectrum shows NCO absent.

EXAMPLE 2

A mixture of 91.5 parts of trimethylolpropane, 273.2 parts of propylene carbonate and 454.9 parts of isophorone diisocyanate is stirred for 2½ hours at 70° C. and then held at 55° C. for 16 hours. The product thus formed contains 10.37% NCO. 809.3 parts of this product is stirred at 33° C. while 201.0 parts of 3,5-dimethylpyrazole is added, followed by 470.8 parts of the monomethyl ether of propylene glycol (Dowanol PM). The temperature rises to 52° C. and a clear solution is formed. The IR spectrum shows NCO absent. Analysis shows only 0.5% of free dimethylpyrazole to be present.

EXAMPLE 3

A mixture of 861 parts of isophorone diisocyanate, 535.95 parts of propylene carbonate and 2.15 parts of Dabco TMR* is stirred and gradually heated. When the temperature reaches 55° C. heating is discontinued. The exothermic reaction raises the temperature to 131° C. in 15 minutes. After cooling to 89° C., 5.8 parts of a 10% solution of Dabco TMR* in propylene carbonate is added. The temperature rises to 90° C. in 8 minutes. After heating to 132° C. it is allowed to cool. 1397.1 parts of this product, the tri-isocyanato-isocyanurate formed from 3 moles of isophorone di-isocyanate as a 61.4% solids solution in propylene carbonate, having an NCO content of 10.94% is stirred while 366.8 parts of 3,5-dimethylpyrazole is added, cooling as required, to keep the temperature below 80° C. followed by 463.4 parts of the monomethyl ether of propylene glycol. The mixture is stirred at 50° C. and a clear solution formed which solution is then allowed to cool. The IR Spectrum shows NCO absent.

* (Reg. Trade Mark) which is N-Hydroxyalkyl Quaternary Ammonium Carboxylate.

EXAMPLE 4

800 parts of pre-polymer from polypropylene glycol of average molecular weight 1000 and 80:20 2,4:2,6-toluene diisocyanate, containing 5.32% NCO and which has been substantially freed from free toluene diisocyanate by thin film evaporation, is stirred while 102.14 parts of 3,5-dimethylpyrazole-is added. After stirring for 1¼ hours the temperature rises from 25° to 46°. The temperature is held at 46° for a further 1¼ hours then raised to 80° during 40 minutes and held at 80° for 110 minutes. The product is a clear pale amber-coloured liquid.

EXAMPLE 5

The preparation referred to in Example 2 above using 3,5-dimethylpyrazole (3,5-DMP) as the blocking agent, was repeated but methyl ethyl ketoxime (MEKO) was used as the blocking agent. The products of each of these preparations was then mixed with the stoichiometric quantity of 1,4-butanediol and 1% dibutyl tin dilaurate was added and then the mixture was coated Qnto steel panels. The coatings were allowed to dry at room temperature for 5 days and then stoved in an oven at the specified temperature for 30 minutes. The panels were then tested for pencil hardness as an indication of cure.

Temperature in ° C. MEKO Blocked 3,5-DMP Blocked 100 Fails HB, no cohesive Fails HB, no cohesive strength strength 120 Fails HB, no cohesive Passes 5H, cohesive strength film 135 Fails HB, no cohesive Passes 7H, cohesive strength film 160 Passes 7H, cohesive Passes 7H, cohesive film film

The above results show an almost 40° C. improvement in cure temperature with the 3,5-dimethylpyrazole blocked polyisocyanate.

EXAMPLE 6

A paint base is made from the following:

parts 1. Xylene 7.90 2. Titanium Dioxide RTC60 *(1) 38.27 3. Additive T.I. *(2) 1.60 4. 10% Acronal 700L Solution in Xylene *(3) 0.40 5. Multiflow *(4) 0.13 6. Synocure 867S *(5) 51.70

METHOD

Charge the Xylene, Additive T.I., 10% Acronal Solution and Multiflow, gradually adding the Titanium Dioxide and half of the Synocure to give sufficient wetting for efficient grinding. Grind under high shear to Hegmann 5, then add the rest of the Synocure.

*(1) RTC60 Tioxide U.K. Ltd *(2) Additive T.I. Bayer U.K. Ltd. *(3) Acronal 700L BASF U.K. Ltd *(4) Multiflow Monsanto PLC *(5) Synocure 867S Cray Valley Products Ltd

A mixture of 58.0 parts of the above described paint base, 22.2 parts of the product from Example 2 and 0.4 part of dibutyltin dilaurate was coated on two steel panels and allowed to dry for seven days at ambient temperature. One panel was stoved for ½ hour at 120°, and the other for ¾ hour at 100° C. Tests for pencil hardness showed that both passed 5H.

Similar results (5H pencil hardness) were obtained using equivalent amounts of the products prepared as described in Example 2 but using instead of 3,5-dimethylpyrazole the equivalent amounts of 4-nitro-3,5-dimethylpyrazole, 4-benzyl-3,5-dimethylpyrazole, methyl 5-methylpyrazole-3-carboxylate, 4-bromo-3,5-dimethylpyrazole, pyrazole, 3-methyl-5-phenylpyrazole and 3,5-dimethylpyrazole-4-carboxanilide (prepared by condensation of hydrazine acetate with diacetoacetanilide). A similar result was also obtained using a product prepared as described in Example 2 but using Pentoxone* (4-methoxy-4-methylpentan-2-one) instead of propylene carbonate. A panel coated with the paint base and stoved for 1 hour at 120° with no crosslinker present failed an HB pencil test.

*Pentoxone—Shell Chemicals PLC 

What is claimed is:
 1. A method of coating a substrate which method comprises (a) spraying or electrodepositing onto said substrate a composition comprising an active hydrogen-containing compound and a blocked polyisocyanate and thereafter (b) heating said blocked polyisocyanate at from 100° C. to 120° C., said blocked polyisocyanate being a compound of formula R—Y_(m) wherein m is an integer greater than 1; R is an m-valent aliphatic, cycloaliphatic, heterocyclic or aromatic residue; and Y is


2. The method of claim 1 wherein the group Y is not directly bonded to an aromatic nucleus in the group R.
 3. The method of claim 1 wherein the group Y is directly bonded to an aromatic nucleus in the group R.
 4. The method of claim 1 wherein said composition is a paint comprising a pigment carrier containing active hydrogen groups, a pigment and said blocked polyisocyanate.
 5. The method of claim 1 which comprises spraying said paint composition onto said substrate and then heating the paint so deposited to cross-link said pigment carrier.
 6. The method of claim 1 wherein m is from 2 to
 6. 7. The method of claim 1 wherein R is a hydrocarbon group optionally substituted by an alkoxy group.
 8. The method of claim 1 wherein R is a divalent radical selected from the group of divalent radicals of formulae:


9. The method of claim 1 wherein, in said blocked polyisocyanate R is a residue of 4,4′-ethylene-bis(phenylisocyanate).
 10. The method of claim 1 wherein, in said blocked polyisocyanate, R is a residue selected from the group consisting of ω,ω′-diisocyanato-1,4-dimethyl cyclohexane, ω,ω′-diisocyanato-1,3-dimethyl cyclohexane, 1-methyl-2,4-diisocyanato cyclohexane, 4,4′-methylene-bis(cyclohexyl isocyanate), and 3-isocyanato-methyl-3,5,5-trimethyl cyclohexyl isocyanate.
 11. The method of claim 1 wherein R is an aromatic residue of an isocyanate compound selected from the group consisting of ω,ω′-diisocyanato-1,3-dimethyl benzene, ω,ω′-diisocyanato-1,4-dimethyl benzene, ω,ω′-diisocyanato-diethyl benzene, ω,ω′-diisocyanato-dimethyl toluene, ω,ω′-diisocyanato-diethyl toluene, 1,3-bis(2-isocyanato-prop-2-yl) benzene, and 1,4-bis(2-isocyanato-prop-2-yl) benzene.
 12. The method of claim 11 wherein R is the residue of 1,3-bis(2-isocyanato-prop-2-yl) benzene.
 13. The method of claim 1 wherein, in said blocked polyisocyanate, R is a residue of a compound selected from the group consisting of ethylene diisocyanate, propylene diisocyanate, tetramethylene diisocyanate, hexamethylene diisocyanate, decamethylene diisocyanate, dodecamethylene diisocyanate, and 2,4,4-trimethylhexamethylene-1,6-diisocyanate.
 14. The method of claim 1 wherein R is selected from the group consisting of phenylene diisocyanate, toluene diisocyanate, naphthylene diisocyanate 4,4′-methylene-bis(phenyl isocyanate), dimer acid diisocyanate, fumaric acid-bis(2-isocyanato ethyl) ester and triphenyl-methane-triisocyanate.
 15. The method of claim 1 wherein said blocked polyisocyanate has a biuret group or an allophanate group.
 16. The method of claim 1 wherein R is a residue of a polyisocyanate reaction product of an isocyanate and an active hydrogen-containing compound selected from the group consisting of water, a lower molecular weight polyol having a molecular weight less than or equal to 300 and a medium molecular weight polyol having a molecular weight greater than 300 and less than
 8000. 17. The method of claim 16 wherein said active hydrogen-containing compound is a lower molecular weight polyol selected from the group consisting of ethylene glycol, propylene glycol, 1,3-butylene glycol, neopentyl glycol, 2,2,4-trimethyl-1,3-pentane diol, hexamethylene glycol, cyclohexane dimethanol hydrogenated bisphenol-A, trimethylol propane, trimethylol ethane, 1,2,6,-hexane triol, glycerine, sorbitol and pentaerythritol.
 18. The method of claim 1 wherein R is selected from a group consisting of a residue of an isocyanurate. 